Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002003 | 0.99 | CYP2C8 (0.46) | CYP2C8ABCG2RAB9AALDH1A1ACHE | |
| SCHEMBL3997189 | 0.87 | MAPT (0.46) | CYP2C8ABCG2ALDH1A1TSHRHPGD | |
| SCHEMBL4001544 | 0.84 | ALDH1A1 (0.48) | CYP2C8ALDH1A1ACHETSHRKMT2A | |
| SCHEMBL4004650 | 0.83 | USP2 (0.44) | CYP2C8ABCG2ALDH1A1ACHETSHR | |
| SCHEMBL4002683 | 0.79 | ACHE (0.44) | RAB9AALDH1A1ACHEHPGDFYN | |
| SCHEMBL4003027 | 0.78 | ALDH1A1 (0.40) | ABCG2RAB9AALDH1A1ACHETSHR | |
| SCHEMBL3996885 | 0.77 | ABCB1 (0.39) | ABCG2RAB9AALDH1A1ACHETSHR | |
| SCHEMBL4008320 | 0.76 | LMNA (0.42) | RAB9AALDH1A1ACHETSHRHPGD | |
| SCHEMBL17667819 | 0.74 | CYP2C8 (0.55) | CYP2C8ABCG2RAB9AALDH1A1NPC1 | |
| SCHEMBL3006020 | 0.71 | CYP2C8 (0.55) | CYP2C8RAB9AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | claimed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | claimed |