Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286936 | 0.84 | ATM (0.62) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL4004092 | 0.83 | ATM (0.45) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL4004085 | 0.83 | ATM (0.45) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL6052462 | 0.81 | ATM (0.69) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL1418969 | 0.80 | ALDH1A1 (0.65) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL1127259 | 0.79 | ATM (1.00) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL6634976 | 0.78 | ATM (0.69) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL3211700 | 0.78 | ATM (0.69) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL28802548 | 0.78 | ATM (0.69) | ATMALDH1A1L3MBTL1CYP1A2POLB | |
| SCHEMBL25240419 | 0.78 | ATM (0.69) | ATMALDH1A1L3MBTL1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074157-A1 | FULLY-MODIFIED PHENYL PYRROLE AMINOGUANIDINES | ACTION PHARMA A/S (DK) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009071101-A1 | N-MODIFIED AMINOGUANIDINE DERIVATIVES | ACTION PHARMA A/S (DK) | 2009-06-11 | — | — | WO | disclosed |