Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14908383 | 0.81 | MAPT (0.47) | ALDH1A1ATMLMNAMAPTNPC1 | |
| SCHEMBL4001880 | 0.80 | ATM (0.65) | ALDH1A1ATMLMNAMAPTNPC1 | |
| SCHEMBL27951608 | 0.77 | MAPT (0.44) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL6052462 | 0.76 | ATM (0.69) | ALDH1A1ATMLMNAL3MBTL1CYP1A2 | |
| SCHEMBL28469213 | 0.76 | EPHX2 (0.48) | ALDH1A1MAPTPPARA | |
| SCHEMBL10059454 | 0.76 | MAPT (0.50) | ATMLMNAMAPTNPC1RAB9A | |
| SCHEMBL25283656 | 0.75 | PIM1 (0.65) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL25251851 | 0.75 | PIM1 (0.65) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL1127259 | 0.74 | ATM (1.00) | ALDH1A1ATMLMNAMAPTL3MBTL1 | |
| SCHEMBL3969097 | 0.74 | NOD1 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | MEDIFIC, INC. (KR) | 2025-02-27 | — | — | US | disclosed |
| EP-4455143-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | Medific, Inc. (KR) | 2024-10-30 | — | — | EP | disclosed |
| CN-118591539-A | Substituted thiazolidinedione derivative compounds and pharmaceutical composition for preventing or treating cancer comprising the same | (株)美迪菲 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |
| US-7994199-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2011-08-09 | — | — | US | disclosed |
| EP-2305664-A1 | Anabaseine derivatives useful in the treatment of neurodegeneratives diseases | Memory Pharmaceuticals Corporation (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2298758-A1 | Anabaseine derivatives useful in the treatment of neurodegenerative diseases | Memory Pharmaceuticals Corporation (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2298759-A1 | Anabaseine derivatives useful in the treatment of neurodegenerative diseases | Memory Pharmaceuticals Corporation (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20100173891-A1 | HETEROCYCLIC COMPOUNDS, METHODS FOR THE PREPARATION THEREOF, AND USES THEREOF | HERBERT BRIAN | 2010-07-08 | — | — | US | disclosed |
| US-7700630-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20090105215-A1 | 3-Quinolin-2-ylmethylene-3,4,5,6-terahydro[2,3']bipyridinyl; for therapy and prophylaxis of psychotic diseases, neurodegenerative diseases involving a dysfunction of the cholinergic system | HERBERT BRIAN | 2009-04-23 | — | — | US | disclosed |
| US-7244745-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORP. (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1531820-A1 | ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Memory Pharmaceuticals Corporation (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040229868-A1 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORP. | 2004-11-18 | — | — | US | disclosed |
| WO-2004019943-A1 | ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MEMORY PHARMACEUTICALS CORPORATION (US) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229868-A1 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | CHRNA1, CHRNA4, CHRNA3 | ALDH1A1 370/4885ATM 4792/4885LMNA 2297/4885 |
| US-20090105215-A1 | 3-Quinolin-2-ylmethylene-3,4,5,6-terahydro[2,3']bipyridinyl; for therapy and prophylaxis of psychotic diseases, neurodegenerative diseases involving a dysfunction of the cholinergic system | CHRNA3, CHRNA2, CHRNA5 | ALDH1A1 1867/4885ATM 4218/4885LMNA 2965/4885 |
| US-20100173891-A1 | HETEROCYCLIC COMPOUNDS, METHODS FOR THE PREPARATION THEREOF, AND USES THEREOF | CHRM3, CHRNA1, CHRNA5 | ALDH1A1 656/4885ATM 4586/4885LMNA 2358/4885 |
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | SREBF1, SREBF2, SP1 | ALDH1A1 1168/4885ATM 914/4885LMNA 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.