Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13963199 | 0.92 | HPGD (0.39) | HPGDRAB9ANPSR1MEN1NPC1 | |
| SCHEMBL4006857 | 0.89 | HPGD (0.41) | HPGDRAB9ANPSR1MEN1NPC1 | |
| SCHEMBL4016104 | 0.88 | AGBL2 (0.41) | HPGDNPSR1MEN1KMT2AMAPT | |
| SCHEMBL13963197 | 0.84 | TRPV1 (0.34) | HPGDNPSR1MAPTALDH1A1TSHR | |
| SCHEMBL4009380 | 0.80 | HPGD (0.39) | HPGDRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL4011125 | 0.80 | ALDH1A1 (0.37) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13962555 | 0.79 | MAPT (0.43) | RAB9ANPSR1MEN1NPC1KMT2A | |
| SCHEMBL13962550 | 0.79 | MAPT (0.37) | RAB9ANPSR1MEN1NPC1KMT2A | |
| SCHEMBL4010973 | 0.77 | ENPP2 (0.41) | HPGDRAB9AMAPTTSHRMAPK1 | |
| SCHEMBL13963201 | 0.77 | PTGDR2 (0.42) | HPGDTSHRTAAR1SMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |