Urea

Urea

SCHEMBL400230

NC(N)=O.Oc1nc(O)nc(O)n1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
ALDH1A1 P00352 1/20 0.46
OR51E2 Q9H255 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ACHE P22303 1/20 0.33
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
PDPK1 O15530 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10823182 0.81 CRBN (0.41) LMNAALDH1A1BLMPMP22
SCHEMBL21385109 0.74
SCHEMBL4778229 0.74
Bromide SCHEMBL7178493 0.74
Water SCHEMBL10576607 0.70
SCHEMBL36692 0.69
SCHEMBL10961190 0.69 LMNA (0.41) LMNA
SCHEMBL34655 0.69 LMNA (0.41) LMNA
Urea SCHEMBL10914180 0.69 CYP1A2 (0.50) LMNAALDH1A1OR51E2TDP1ACHE
Urea SCHEMBL15483993 0.69 CYP1A2 (0.50) LMNAALDH1A1OR51E2TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3487957-B1 FLAME RETARDANT MIXTURES, THE PRODUCTION AND THE USE THEREOF CLARIANT INT LTD (CH) 2023-04-12 EP claimed
EP-4141059-A1 DIORGANYLPHOSPHINIC SALTS HAVING EXCEPTIONAL SURFACE STRUCTURE Clariant International Ltd (CH) 2023-03-01 EP claimed
US-11312910-B2 Diorganylphosphinic acid salts, method for the production thereof and the use thereof CLARIANT INTERNATIONAL LTD (CH) 2022-04-26 US claimed
EP-3487861-B1 DIORGANYLPHOSPHINIC ACID SALTS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2021-12-01 EP claimed
CN-108779347-B Halogen-free fire-retardant coating capable of forming barrier layer and use thereof 科莱恩塑料和涂料有限公司 2021-09-21 CN claimed
CN-108291050-B Polymeric flame retardant mixtures 科莱恩塑料和涂料有限公司 2021-06-25 CN claimed
US-11028324-B2 Flame retardant mixtures, the production and the use thereof CLARIANT PLASTICS & COATINGS LTD (CH) 2021-06-08 US claimed
EP-3426731-B1 HALOGEN-FREE, INTUMESCENT FIRE-PROOF COATING, AND USE THEREOF CLARIANT INT LTD (CH) 2021-05-12 EP claimed
CN-107637605-B Flame retardant mixtures, their preparation and their use 科莱恩塑料和涂料有限公司 2021-01-05 CN claimed
CN-109081944-B Dialkyl dithiophosphate flame retardant and application thereof 浙江大学 2020-05-12 CN claimed
EP-0533610-B1 A plant for producing cyanuric acid and process therefor PATENTES NOVEDADES SA (ES) 1995-09-06 EP claimed
US-5245033-A PROCESS FOR PRODUCING CYANURIC ACID PATENTES Y NOVADADES, S.L. (ES) 1993-09-14 US claimed
EP-0533610-A1 A plant for producing cyanuric acid and process therefor PATENTES Y NOVEDADES S.L. (ES) 1993-03-24 EP claimed
US-5189085-A Polyamides, polyurethanes, homo or coacrylonitrile plastics CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1993-02-23 US claimed
US-4822624-A STABLE AQUEOUS SOLUTION OF POLYUREAS, UREASE ENZYME, AMMONIA INHIBITS MICROORGANISMS UNION OIL COMPANY OF CALIFORNIA (US) 1989-04-18 US claimed
EP-0287191-A1 Synthesis of urea cyanurate OLIN CORPORATION (US) 1988-10-19 EP claimed
US-4725684-A UREA AND CYANURIC ACID, BELOW MELTING POINT OF UREA OLIN CORPORATION (US) 1988-02-16 US claimed
US-4580633-A Increasing the flow of fluids through a permeable formation UNION OIL COMPANY OF CALIFORNIA (US) 1986-04-08 US claimed
US-4426396-A UREASE, AMMONIA AND A UREA COMPOUND UNION OIL COMPANY OF CALIFORNIA (US) 1984-01-17 US claimed
US-4018769-A Urea cyanurate manufacture UNION OIL COMPANY OF CALIFORNIA (US) 1977-04-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312910-B2 Diorganylphosphinic acid salts, method for the production thereof and the use thereof PPIP5K2, DCPS, FDPS LMNA 4078/4885ALDH1A1 2853/4885OR51E2 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.