Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MPO | P05164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171815 | 0.81 | KDM4E (0.57) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL2345028 | 0.80 | KDM4E (0.52) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL4008467 | 0.77 | KDM4E (0.45) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL28851024 | 0.76 | KDM4E (0.47) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL4004764 | 0.74 | FAAH (0.43) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL2989555 | 0.73 | CYP1A2 (0.60) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL30637340 | 0.73 | KDM4E (0.55) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL1543956 | 0.73 | KDM4E (0.55) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL6937622 | 0.72 | METAP2 (0.50) | KDM4EMPOCYP3A4CYP1A2ADORA3 | |
| SCHEMBL11155559 | 0.71 | KDM4E (0.49) | KDM4EMPOCYP3A4CYP1A2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |