Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503060 | 0.78 | NAPRT (0.52) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7554003 | 0.78 | KMT2A (0.45) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1415951 | 0.75 | KDM4E (0.49) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7554228 | 0.75 | KMT2A (0.42) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2988329 | 0.75 | NAPRT (0.48) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27854800 | 0.74 | KDM4E (0.47) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1648241 | 0.73 | NAPRT (0.46) | NOS1KDM4ENOS3NOS2KMT2A | |
| SCHEMBL7550214 | 0.73 | HDAC3 (0.44) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4008468 | 0.72 | KDM4E (0.42) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4004765 | 0.72 | NAAA (0.47) | KDM4EKMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |