Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425931 | 0.90 | GPR119 (0.37) | — | |
| SCHEMBL2428962 | 0.75 | TACR1 (0.30) | — | |
| SCHEMBL4007696 | 0.75 | CTSK (0.35) | MCHR1OPRD1OPRK1SMYD3 | |
| SCHEMBL2427997 | 0.75 | DGAT1 (0.31) | — | |
| SCHEMBL2431443 | 0.74 | TACR1 (0.36) | — | |
| SCHEMBL2431447 | 0.74 | TACR1 (0.36) | — | |
| SCHEMBL2426430 | 0.74 | TACR1 (0.35) | — | |
| SCHEMBL2428513 | 0.74 | TACR1 (0.35) | — | |
| SCHEMBL2428891 | 0.74 | TACR1 (0.34) | — | |
| SCHEMBL2427833 | 0.73 | TACR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009411-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |