Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002973 | 0.83 | HRH2 (0.37) | TSHRTDP1L3MBTL1ALDH1A1HRH2 | |
| SCHEMBL3760642 | 0.80 | MAPK1 (0.39) | SIGMAR1POLBMAPK1CHRM2CHRM4 | |
| SCHEMBL3762318 | 0.75 | SIGMAR1 (0.43) | ALDH1A1SIGMAR1KMT2APOLBGAA | |
| SCHEMBL27627013 | 0.74 | TSHR (0.45) | TSHRTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3895345 | 0.70 | SIGMAR1 (0.41) | ALDH1A1SIGMAR1SMN1; SMN2KMT2APOLB | |
| SCHEMBL17017 | 0.70 | POLB (0.63) | TSHRTDP1ALDH1A1HRH2HRH1 | |
| SCHEMBL5820669 | 0.70 | POLB (0.63) | TSHRTDP1ALDH1A1HRH2HRH1 | |
| SCHEMBL18760256 | 0.70 | POLB (0.63) | TSHRTDP1ALDH1A1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL1111003 | 0.68 | POLB (0.61) | TSHRTDP1ALDH1A1HRH2HRH1 | |
| SCHEMBL4082478 | 0.68 | POLB (0.61) | TSHRTDP1ALDH1A1HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |