Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002967 | 0.83 | TSHR (0.36) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| SCHEMBL3760646 | 0.80 | HPGD (0.36) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL3762322 | 0.73 | GAA (0.43) | POLBALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5820669 | 0.72 | POLB (0.63) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| SCHEMBL17017 | 0.72 | POLB (0.63) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| SCHEMBL18760256 | 0.72 | POLB (0.63) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| Hydrochloric Acid SCHEMBL1111003 | 0.71 | POLB (0.61) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| Potassium SCHEMBL30906131 | 0.71 | POLB (0.61) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| SCHEMBL4082478 | 0.71 | POLB (0.61) | HRH2HRH1SMN1; SMN2LMNAPOLB | |
| SCHEMBL5667296 | 0.68 | LMNA (0.57) | HRH2HRH1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |