Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40034 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| SCHEMBL134643 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| SCHEMBL15384851 | 0.98 | CYP3A4 (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL132158 | 0.98 | TSHR (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| SCHEMBL17919051 | 0.98 | CYP3A4 (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| SCHEMBL1688457 | 0.98 | CYP3A4 (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL134642 | 0.98 | TSHR (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL1899822 | 0.98 | TSHR (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| SCHEMBL16946146 | 0.98 | CYP3A4 (0.45) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL15206077 | 0.96 | TSHR (0.44) | CYP3A4CYP2D6TSHRCYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3967714-B1 | VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES | SEKISUI CHEMICAL CO LTD (JP) | 2026-01-07 | — | — | EP | claimed |
| US-11753378-B2 | Ketamine compounds and processes for making and using them | ZEVRA THERAPEUTICS, INC. (US) | 2023-09-12 | — | — | US | claimed |
| US-20220348544-A1 | KETAMINE COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2022-11-03 | — | — | US | claimed |
| CN-112010855-B | Hexacyclic piperazinedione compounds, preparation, biological activity and application thereof | 首都医科大学 | 2021-06-08 | — | — | CN | claimed |
| CN-112010855-A | Hexacyclic piperazinedione compounds, preparation, biological activity and application thereof | 首都医科大学 | 2020-12-01 | — | — | CN | claimed |
| CN-105555783-B | Include the autotaxin inhibitors of heteroaromatic rings benzyl amide ring core | 诺华股份有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-105555783-A | Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core | NOVARTIS AG | 2016-05-04 | — | — | CN | claimed |
| CN-104086479-B | 5-((2-carboxypiperidin-1-base) methyl) m-phthalic acid and synthetic method thereof and application | TIANJIN PUMAO SCIENCE & TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-104086479-A | 5-((2-carboxypiperidin-1-yl)methyl)isophthalic acid as well as synthetic method and application thereof | TIANJIN PUMAO SCIENCE & TECHNOLOGY DEV CO LTD | 2014-10-08 | — | — | CN | claimed |
| CN-101679384-B | Amide derivatives for inhibiting cancer cell growth | HANMI PHARM IND CO LTD | 2013-10-16 | — | — | CN | claimed |
| CN-102186851-B | Triazolopyridine compounds as pim kinase inhibitors | ARRAY BIOPHARMA INC | 2013-06-12 | — | — | CN | claimed |
| CN-1665801-B | Anti tubercular drug: compositions and methods | DEPT OF HEALTH AND HUMAN SERVI | 2011-05-11 | — | — | CN | claimed |
| CN-101679384-A | Novel amide derivatives for inhibiting the growth of cancer cells | HANMI PHARM IND CO LTD | 2010-03-24 | — | — | CN | claimed |
| EP-1948167-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | claimed |
| US-20070232559-A1 | 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2007-10-04 | — | — | US | claimed |
| WO-2007045980-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | claimed |
| CN-1738805-A | N- (1-benzyl-2-oxo-2- (1-piperazinyl) ethyl) -1-piperidincarboxamid-derivatives and related compounds use as CGRP-antagonists for treating a headache | BOEHRINGER INGELHEIM INT (DE) | 2006-02-22 | — | — | CN | claimed |
| US-4493828-A | Use of thyrotropin releasing hormone and related peptides as poultry growth promotants | MERCK & CO., INC. (US) | 1985-01-15 | — | — | US | claimed |
| EP-3483142-B1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | BEIJING MAXINOVEL PHARMACEUTICALS CO LTD (CN) | 2025-10-15 | — | — | EP | disclosed |
| US-3984419-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753378-B2 | Ketamine compounds and processes for making and using them | OPRK1, GRIK3, GRIN3B | CYP3A4 1618/4885CYP2D6 425/4885TSHR 4770/4885 |
| US-20070232559-A1 | 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF | ADORA2A, ADORA3, ADORA1 | CYP3A4 1117/4885CYP2D6 1452/4885TSHR 203/4885 |
| US-20220348544-A1 | KETAMINE COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM | OPRK1, GRIK3, GRIN3B | CYP3A4 1618/4885CYP2D6 425/4885TSHR 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.