Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23883211 | 0.79 | DRD2 (0.55) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL5820396 | 0.79 | DRD2 (0.55) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL3995719 | 0.78 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL5323013 | 0.77 | DRD2 (0.43) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL667229 | 0.71 | CCR3 (0.68) | OPRL1DRD2DRD3MEN1ALDH1A1 | |
| SCHEMBL5321289 | 0.69 | KDM4E (0.48) | OPRM1OPRL1OPRD1OPRK1CCR1 | |
| SCHEMBL6185872 | 0.69 | OPRM1 (0.62) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL664827 | 0.68 | CCR3 (0.58) | OPRL1DRD2DRD3MEN1ALDH1A1 | |
| SCHEMBL3139402 | 0.67 | DRD2 (0.73) | OPRM1DRD2DRD3MEN1TSHR | |
| SCHEMBL8985999 | 0.67 | OPRL1 (0.55) | OPRM1OPRL1OPRD1OPRK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874730-A4 | SUBSTITUTED BUTYROPHENONE DERIVATIVES | CLERA INC (CA) | 2009-06-10 | — | — | EP | claimed |
| EP-1874730-A1 | SUBSTITUTED BUTYROPHENONE DERIVATIVES | Clera Inc. (CA) | 2008-01-09 | — | — | EP | claimed |
| WO-2006116848-A1 | SUBSTITUTED BUTYROPHENONE DERIVATIVES | CLERA INC. (CA) | 2006-11-09 | — | — | WO | claimed |
| EP-1874730-A4 | SUBSTITUTED BUTYROPHENONE DERIVATIVES | CLERA INC (CA) | 2009-06-10 | — | — | EP | disclosed |
| EP-1874730-A1 | SUBSTITUTED BUTYROPHENONE DERIVATIVES | Clera Inc. (CA) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006116848-A1 | SUBSTITUTED BUTYROPHENONE DERIVATIVES | CLERA INC. (CA) | 2006-11-09 | — | — | WO | disclosed |