SCHEMBL723636

SCHEMBL723636

C#CN1C(=O)C=CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8471148 0.71
SCHEMBL4004252 0.67 MGLL (0.36)
SCHEMBL10606609 0.66
SCHEMBL718144 0.65 MGLL (0.41)
SCHEMBL379033 0.63 MAOA (0.47)
SCHEMBL9856415 0.62
SCHEMBL10889784 0.62
SCHEMBL157324 0.60 MGLL (0.50)
SCHEMBL9407360 0.60 MGLL (0.42)
SCHEMBL717282 0.59 BRD4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3221698-B1 POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF Global Life Sciences Solutions Operations UK Ltd (GB) 2021-02-17 EP claimed
EP-2922818-B1 HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULES HANGZHOU DAC BIOTECH CO LTD (CN) 2018-09-05 EP claimed
US-5189129-A High temperature polymer from maleimide-acetylene terminated monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1993-02-23 US claimed
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20150147395-A1 COMPOUNDS AND MEDICAL DEVICES ACTIVATED WITH SOLVOPHOBIC LINKERS SOFRADIM PRODUCTION (FR) 2015-05-28 US disclosed
US-8969473-B2 Compounds and medical devices activated with solvophobic linkers SOFRADIM PRODUCTION (FR) 2015-03-03 US disclosed
EP-2448929-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-05-09 EP disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed
WO-2011001052-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2011-01-06 WO disclosed
US-5189129-A High temperature polymer from maleimide-acetylene terminated monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1993-02-23 US disclosed
US-5189129-A High temperature polymer from maleimide-acetylene terminated monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1993-02-23 US disclosed
US-5189129-A High temperature polymer from maleimide-acetylene terminated monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1993-02-23 US disclosed