Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14342877 | 0.85 | KMO (0.47) | HSD11B1CNR2KMOSCN9ACYP1A2 | |
| SCHEMBL4003469 | 0.80 | TAAR1 (0.35) | KMOSCN9AP2RX7TDP1ALDH1A1 | |
| SCHEMBL16872757 | 0.79 | HSD11B1 (0.49) | HSD11B1CNR2KMOSCN9AMPL | |
| SCHEMBL3539249 | 0.74 | HSD11B1 (0.41) | HSD11B1CNR2SCN9ACES1 | |
| SCHEMBL3995888 | 0.74 | JAK2 (0.39) | KMOSCN9AMPLCYP1A2CYP3A4 | |
| SCHEMBL3999983 | 0.74 | ALOX5AP (0.40) | SCN9A | |
| SCHEMBL3988160 | 0.73 | HSD11B1 (0.43) | HSD11B1CNR2KMOSCN9AMPL | |
| SCHEMBL6067687 | 0.73 | HSD11B1 (0.55) | HSD11B1CNR2SCN9AMPLP2RX7 | |
| SCHEMBL2750708 | 0.72 | CNR2 (0.47) | HSD11B1CNR2SCN9AMPLP2RX7 | |
| SCHEMBL3534868 | 0.71 | HSD11B1 (0.44) | HSD11B1CNR2SCN9AMPLCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |