Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14342877 | 0.81 | KMO (0.47) | SCN9AKMOALDH1A1TDP1 | |
| SCHEMBL4004584 | 0.80 | HSD11B1 (0.42) | TAAR1SCN9AKMOALDH1A1TDP1 | |
| SCHEMBL2752979 | 0.76 | GABRA1 (0.33) | TDP1 | |
| SCHEMBL3996445 | 0.75 | NOTUM (0.46) | SCN9APDK2KMO | |
| SCHEMBL3995888 | 0.72 | JAK2 (0.39) | SCN9ASCN5AKMOPARP1TDP1 | |
| SCHEMBL3999983 | 0.72 | ALOX5AP (0.40) | SCN9A | |
| SCHEMBL2752817 | 0.72 | NOS3 (0.38) | PDK2ALDH1A1TDP1 | |
| SCHEMBL2752501 | 0.72 | KDM4E (0.30) | TDP1 | |
| SCHEMBL2753808 | 0.72 | NR4A2 (0.35) | TAAR1PARP1TDP1 | |
| SCHEMBL2184027 | 0.71 | KIF11 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |