Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995888 | 0.88 | JAK2 (0.39) | ALOX5APFEN1CES2ARCBFB | |
| SCHEMBL16457762 | 0.84 | NPC1 (0.41) | CBFBCYP2C9SCN9A | |
| SCHEMBL14342877 | 0.81 | KMO (0.47) | SCN9A | |
| SCHEMBL1206412 | 0.80 | CBFB (0.50) | ALOX5APFEN1TRPV3CBFBPOLQ | |
| SCHEMBL19072713 | 0.79 | NOS3 (0.47) | ALOX5APFEN1TRPV3ABCC8KCNJ11 | |
| SCHEMBL2184027 | 0.76 | KIF11 (0.47) | TOP1GSK3B | |
| SCHEMBL3541438 | 0.75 | EDNRB (0.40) | ALOX5APFEN1TRPV3ABCC8KCNJ11 | |
| SCHEMBL19072710 | 0.75 | FEN1 (0.45) | ALOX5APFEN1TRPV3ABCC8KCNJ11 | |
| SCHEMBL3993194 | 0.74 | TRPV3 (0.41) | ALOX5APFEN1TRPV3ABCC8KCNJ11 | |
| SCHEMBL4004584 | 0.74 | HSD11B1 (0.42) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |