SCHEMBL4005975

SCHEMBL4005975

C1=CC2(Oc3ccccc3C=C2c2ccccc2)Oc2cc(N(Cc3ccccc3)Cc3ccccc3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
HIF1A Q16665 2/20 0.32
EPAS1 Q99814 2/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6701609 1.00 CYP2C19 (0.35) CYP2C19HTTNPSR1CRHBPCRHR2
SCHEMBL11268720 0.92 CYP2C19 (0.34) CYP2C19CRHBPCRHR2HIF1AEPAS1
SCHEMBL3877465 0.89 CA12 (0.33) HTTHIF1AEPAS1
SCHEMBL11280803 0.85 CA12 (0.35) HTTHIF1AEPAS1
SCHEMBL9333313 0.84 HTR2C (0.32)
SCHEMBL6262175 0.83 CYP2C19 (0.36) CYP2C19HTTNPSR1CRHBPCRHR2
SCHEMBL8765040 0.83 CYP2C19 (0.36) CYP2C19HTTNPSR1CRHBPCRHR2
SCHEMBL11264128 0.81 CA12 (0.33) HTT
SCHEMBL11259985 0.81 CA12 (0.33) HTT
SCHEMBL8685158 0.81 HTR2C (0.41) HTTNPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083262-B1 THERMAL RECORDING MATERIALS APPVION OPERATIONS INC (US) 2019-06-26 EP claimed
US-9126451-B2 Thermal recording materials APPVION, INC. (US) 2015-09-08 US claimed
US-20150165806-A1 THERMAL RECORDING MATERIALS APPVION, INC. (US) 2015-06-18 US claimed
EP-0846569-B1 Thermally-Responsive Record Material APPLETON PAPER INC (US) 2002-02-06 EP claimed
EP-0165041-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-01-04 EP claimed
US-4586061-A CONTAINING CHROMOGENIC MATERIAL AND A BISPHENOL DEVELOPER APPLETON PAPERS INC. (US) 1986-04-29 US claimed
US-4520379-A CHROMOGEN, ACIDIC DEVELOPER AND BINDER ON SUPPORT APPLETON PAPERS INC. (US) 1985-05-28 US claimed
EP-2969580-B1 THERMALLY-RESPONSIVE RECORD MATERIAL APPVION OPERATIONS INC (US) 2020-07-29 EP disclosed
US-20190193447-A1 PRINTABLE AND SCUFF RESISTANT SILICONE RELEASE COATING FOR LINERLESS THERMALLY-RESPONSIVE RECORD MATERIAL WC APV OPCO, LLC 2019-06-27 US disclosed
EP-3083262-B1 THERMAL RECORDING MATERIALS APPVION OPERATIONS INC (US) 2019-06-26 EP disclosed
US-20170340955-A1 THERMALLY IMAGEABLE SUBSTRATE WITH ENCAPSULATED COREACTANT APPVION OPERATIONS, INC. 2017-11-30 US disclosed
US-9534156-B2 Linerless record material APPVION, INC. (US) 2017-01-03 US disclosed
EP-3083262-A1 THERMAL RECORDING MATERIALS APPVION, INC. (US) 2016-10-26 EP disclosed
EP-0846569-A1 Thermally-Responsive Record Material APPLETON PAPERS INC. (US) 1998-06-10 EP disclosed
EP-0517380-B1 Thermally-reponsive record material APPLETON PAPER INC (US) 1997-08-27 EP disclosed
EP-0414509-B1 Heat sensitive record material APPLETON PAPER INC (US) 1994-09-21 EP disclosed
EP-0517380-A1 Thermally-reponsive record material APPLETON PAPERS INC. (US) 1992-12-09 EP disclosed
US-5164357-A THERMALLY-RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1992-11-17 US disclosed
EP-0414509-A2 Heat sensitive record material APPLETON PAPERS INC. (US) 1991-02-27 EP disclosed
EP-0311790-A1 Marked mineral oil product, and process to mark mineral oil products BASF Aktiengesellschaft (DE) 1989-04-19 EP disclosed