SCHEMBL400643

SCHEMBL400643

Oc1c(Cl)cc(C2(c3cc(Cl)c(O)c(Cl)c3)CC3CCC2C3)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 8/20 0.48
HSD11B1 P28845 1/20 0.35
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TTR P02766 1/20 0.33
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
RECQL P46063 1/20 0.33
P2RX5 Q93086 1/20 0.33
P2RX4 Q99571 1/20 0.33
P2RX7 Q99572 1/20 0.33
P2RX2 Q9UBL9 1/20 0.33
THRB P10828 1/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2D6 P10635 1/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9805640 0.80 ALOX5AP (0.48) ALOX5APHSD11B1TSHRHSD17B10ALOX5
SCHEMBL10051858 0.78 ALOX5AP (0.49) ALOX5APHSD11B1ALOX5
SCHEMBL259032 0.74 ALOX5AP (0.63) ALOX5APHSD11B1ALOX5
SCHEMBL12954721 0.74 ALOX5AP (0.63) ALOX5APHSD11B1ALOX5
SCHEMBL14580032 0.73 ALOX5AP (0.38) ALOX5APHSD11B1ALOX5ALDH1A1
SCHEMBL3973784 0.72 HSD17B10 (0.38) HSD11B1TSHRHSD17B10TTRALDH1A1
SCHEMBL899767 0.70 ALOX5AP (0.55) ALOX5APHSD11B1ALOX5SMN1; SMN2
SCHEMBL790990 0.69 ALOX5AP (0.67) ALOX5APHSD11B1ALOX5
SCHEMBL3975973 0.68 MEN1 (0.42) TSHRHSD17B10TTRALDH1A1CYP3A4
SCHEMBL12920588 0.68 ALOX5AP (0.56) ALOX5APHSD11B1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084109-A1 THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING BASF SE (DE) 2024-03-14 US disclosed
US-20240010812-A1 FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME STRATASYS, INC. 2024-01-11 US disclosed
EP-4271550-A1 THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING BASF SE (DE) 2023-11-08 EP disclosed
EP-4247618-A1 FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME BASF SE (DE) 2023-09-27 EP disclosed
CN-116635238-A Thermoplastic powdery composition for three-dimensional printing 巴斯夫欧洲公司 2023-08-22 CN disclosed
WO-2022144160-A1 THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING BASF SE (DE) 2022-07-07 WO disclosed
WO-2022106402-A1 FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME BASF SE (DE) 2022-05-27 WO disclosed
CN-107278219-B Deoxybenzoin-containing flame-retardant polymer composition 巴斯夫欧洲公司 2021-03-05 CN disclosed
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants BASF SE (DE) 2019-09-17 US disclosed
US-10407539-B2 Deoxybenzoin containing flame retardant polymer compositions BASF SE (DE) 2019-09-10 US disclosed
WO-2007093513-A1 AROMATIC SULPHONATE FLAME RETARDANT COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-23 WO disclosed
WO-2007020211-A1 POLYCARBONATE FLAME RETARDENT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-02-22 WO disclosed
EP-0666837-B1 DEPOLYMERIZATION OF SUBSTANTIALLY AMORPHOUS POLYESTERS EASTMAN CHEM CO (US) 1997-01-02 EP disclosed
EP-0666837-A1 DEPOLYMERIZATION OF SUBSTANTIALLY AMORPHOUS POLYESTERS. EASTMAN CHEM CO (US) 1995-08-16 EP disclosed
EP-0505473-B1 ESTER HYDROLYSIS AND DEPOLYMERIZATION OF POLYESTER AND POLYCARBONATE POLYMERS EASTMAN KODAK CO (US) 1994-07-20 EP disclosed
US-5328982-A Forming glycols and diacids by contacting with methanol or glycol, aprotic acid and alkoxide or hydroxide EASTMAN CHEMICAL COMPANY (US) 1994-07-12 US disclosed
WO-1994010121-A1 DEPOLYMERIZATION OF SUBSTANTIALLY AMORPHOUS POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1994-05-11 WO disclosed
EP-0505473-A1 ESTER HYDROLYSIS AND DEPOLYMERIZATION OF POLYESTER AND POLYCARBONATE POLYMERS. EASTMAN KODAK CO (US) 1992-09-30 EP disclosed
US-5045122-A Alcohol or glycol, aprotic solvent, alkoxide or hydroxide EASTMAN KODAK COMPANY (US) 1991-09-03 US disclosed
WO-1991009004-A1 ESTER HYDROLYSIS AND DEPOLYMERIZATION OF POLYESTER AND POLYCARBONATE POLYMERS EASTMAN KODAK COMPANY (US) 1991-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants PFAS, PCBP1, DDT ALOX5AP 874/4885HSD11B1 3069/4885TSHR 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.