SCHEMBL3973784

SCHEMBL3973784

Oc1c(Cl)cc(C2(c3cc(Cl)c(O)c(Cl)c3)C3CC4CC(C3)CC2C4)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.38
TSHR P16473 3/20 0.38
TTR P02766 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38
P2RX5 Q93086 1/20 0.36
P2RX4 Q99571 1/20 0.36
P2RX7 Q99572 1/20 0.36
P2RX2 Q9UBL9 1/20 0.36
THRB P10828 1/20 0.35
HSD11B1 P28845 6/20 0.35
CYP2C9 P11712 2/20 0.34
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976002 0.80 MEN1 (0.42) HSD17B10TSHRALDH1A1HSD11B1SMN1; SMN2
SCHEMBL3976140 0.77 CYP3A4 (0.38) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL2047938 0.77 ACHE (0.44) HSD11B1CYP2C9MEN1POLBGAA
SCHEMBL3976244 0.77 HSD11B1 (0.38) HSD11B1MEN1POLBGAAGFER
SCHEMBL10051861 0.74 HSD11B1 (0.33) HSD11B1MEN1KMT2A
SCHEMBL3978480 0.74 PTPN1 (0.40) CYP3A4RECQLHSD11B1CYP2C9CYP1A2
SCHEMBL3975973 0.73 MEN1 (0.42) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL3977574 0.73 CYP1A2 (0.36) ALDH1A1CYP3A4HSD11B1CYP2C9CYP1A2
SCHEMBL400643 0.72 ALOX5AP (0.48) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL4584573 0.70 KDM4E (0.43) ALDH1A1HSD11B1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed