SCHEMBL899767

SCHEMBL899767

Cc1cc(C2(c3ccc(O)c(C)c3)CC3CCC2C3)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 8/20 0.55
ESR1 P03372 5/20 0.45
ESR2 Q92731 5/20 0.45
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 2/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
ALOX5 P09917 1/20 0.38
HSD11B1 P28845 1/20 0.38
PDE10A Q9Y233 1/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
XBP1 P17861 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979156 0.92 ALOX5AP (0.51) ALOX5APESR1ESR2MEN1KMT2A
SCHEMBL790026 0.82 ALOX5AP (0.45) ALOX5APHSD11B1LMNATDP1
SCHEMBL12286910 0.81 ALOX5AP (0.51) ALOX5APESR1ESR2MEN1KMT2A
SCHEMBL259032 0.77 ALOX5AP (0.63) ALOX5APESR1ESR2ALOX5HSD11B1
SCHEMBL12954721 0.77 ALOX5AP (0.63) ALOX5APESR1ESR2ALOX5HSD11B1
SCHEMBL12948105 0.77 ALOX5AP (0.56) ALOX5APESR2KMT2AALOX5HSD11B1
SCHEMBL31030078 0.74 ESR1 (0.50) ALOX5APESR1ESR2MEN1KMT2A
SCHEMBL1238135 0.74 ESR1 (0.50) ALOX5APESR1ESR2MEN1KMT2A
SCHEMBL8512609 0.72 ESR1 (0.42) ESR1ESR2MEN1KMT2APOLB
SCHEMBL14829735 0.72 MEN1 (0.71) ESR1ESR2MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130323640-A1 Preparation of Norbornane-based PAC Ballasts SUMITOMO BAKELITE CO., LTD. (JP) 2013-12-05 US claimed
US-9777184-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-10-03 US disclosed
US-9777184-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-10-03 US disclosed
US-9715041-B2 Optical film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9715041-B2 Optical film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9715040-B2 Optical film and manufacturing method thereof, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9715040-B2 Optical film and manufacturing method thereof, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-20160376462-A1 (METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-29 US disclosed
US-20160091630-A1 OPTICAL FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-31 US disclosed
US-20160091630-A1 OPTICAL FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-31 US disclosed
US-8329852-B2 Copolycarbonates having improved surface hardness BAYER MATERIALSCIENCE AG (DE) 2012-12-11 US disclosed
US-8329852-B2 Copolycarbonates having improved surface hardness BAYER MATERIALSCIENCE AG (DE) 2012-12-11 US disclosed
US-20120135352-A1 Preparation of Norbornane-based PAC Ballasts PROMERUS LLC (US) 2012-05-31 US disclosed
US-20120135352-A1 Preparation of Norbornane-based PAC Ballasts PROMERUS LLC (US) 2012-05-31 US disclosed
US-20120135352-A1 Preparation of Norbornane-based PAC Ballasts PROMERUS LLC (US) 2012-05-31 US disclosed
WO-2012044719-A1 NORBORNANE-BASED PAC BALLAST AND POSITIVE-TONE PHOTOSENSITIVE RESIN COMPOSITION ENCOMPASSING THE PAC PROMERUS LLC (US) 2012-04-05 WO disclosed
US-20110230626-A1 COPOLYCARBONATES HAVING IMPROVED SURFACE HARDINESS BAYER MATERIALSCIENCE AG (DE) 2011-09-22 US disclosed
US-20110230626-A1 COPOLYCARBONATES HAVING IMPROVED SURFACE HARDINESS BAYER MATERIALSCIENCE AG (DE) 2011-09-22 US disclosed
US-20110144284-A1 POLYCARBONATE COMPOSITIONS HAVING IMPROVED SURFACE HARDNESS BAYER MATERIALSCIENCE AG (DE) 2011-06-16 US disclosed
US-20110144284-A1 POLYCARBONATE COMPOSITIONS HAVING IMPROVED SURFACE HARDNESS BAYER MATERIALSCIENCE AG (DE) 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135352-A1 Preparation of Norbornane-based PAC Ballasts NBAS, PHB2, BDNF ALOX5AP 1038/4885ESR1 2990/4885ESR2 4139/4885
US-20160376462-A1 (METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE YTHDC1, ARID2, YTHDF1 ALOX5AP 825/4885ESR1 1238/4885ESR2 3508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.