Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4980531 | 0.85 | POLB (0.61) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL7803748 | 0.83 | ERN1 (0.54) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL16975394 | 0.83 | ALDH1A1 (0.56) | ERN1ALDH1A1TSHRPOLBL3MBTL1 | |
| SCHEMBL786831 | 0.82 | ALDH1A1 (0.56) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL15283303 | 0.82 | ALDH1A1 (0.56) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL51277 | 0.82 | GPR35 (0.60) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL7755626 | 0.81 | TDP1 (0.52) | ERN1ALDH1A1TSHRGAATHRB | |
| SCHEMBL11509750 | 0.81 | APP (0.56) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL4231830 | 0.80 | ALDH1A1 (0.58) | ERN1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL216753 | 0.80 | GPR35 (0.58) | ERN1GPR35ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |