Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034316 | 0.84 | KDM4E (0.44) | MAPTRAB9AALDH1A1LMNANPSR1 | |
| SCHEMBL4011709 | 0.83 | MAPT (0.41) | MAPTRAB9AALDH1A1LMNATDP1 | |
| SCHEMBL8040773 | 0.81 | MEN1 (0.44) | RAB9AALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL4010260 | 0.76 | ATM (0.45) | MAPTRAB9AALDH1A1LMNATDP1 | |
| SCHEMBL4011731 | 0.76 | MAPT (0.41) | MAPTRAB9AALDH1A1LMNATDP1 | |
| SCHEMBL4009317 | 0.75 | CNR1 (0.40) | MAPTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL4007693 | 0.73 | CNR1 (0.42) | RAB9AALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL4016764 | 0.73 | ATM (0.53) | MAPTRAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL4014170 | 0.73 | MAPT (0.43) | MAPTRAB9AALDH1A1LMNATDP1 | |
| SCHEMBL4011727 | 0.72 | RAB9A (0.41) | MAPTRAB9AALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |