Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421461 | 0.74 | ABCG2 (0.87) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL16470197 | 0.71 | CA12 (0.54) | MAPTALDH1A1CYP3A4HPGDHSD17B10 | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL4285872 | 0.71 | KDM4E (1.00) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL30139617 | 0.71 | KDM4E (1.00) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL15676607 | 0.71 | KDM4E (1.00) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL10469365 | 0.69 | IMPDH2 (0.49) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8309264 | 0.69 | ABCG2 (0.67) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL31723152 | 0.68 | MEN1 (0.72) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28425332 | 0.68 | MEN1 (0.72) | ABCG2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL3008129 | 0.68 | CYP2C8 (0.54) | ABCG2MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |