SCHEMBL4009364

SCHEMBL4009364

c1cnc2c(c1)c1nccnc1c1cccnc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 0.67
L3MBTL1 Q9Y468 3/20 0.67
NPC1 O15118 1/20 0.67
KDM4E B2RXH2 4/20 0.52
CCR1 P32246 3/20 0.52
CCR8 P51685 3/20 0.52
MAPT P10636 3/20 0.52
LMNA P02545 3/20 0.52
HTT P42858 2/20 0.52
CYP3A4 P08684 2/20 0.52
GMNN O75496 1/20 0.52
TP53 P04637 1/20 0.52
MMP2 P08253 1/20 0.52
CYP2D6 P10635 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52
MMP8 P22894 1/20 0.52
THPO P40225 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29849953 1.00 HSP90AA1 (0.67) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL30128213 0.97 HSP90AA1 (0.64) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL18174540 0.97 HSP90AA1 (0.64) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL3070322 0.94 HSP90AA1 (0.61) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL6045195 0.92 HSP90AA1 (0.58) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL26749762 0.91 HSP90AA1 (0.64) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL17523388 0.91 HSP90AA1 (0.64) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL4993117 0.91 HSP90AA1 (0.64) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL5473648 0.90 HSP90AA1 (0.62) HSP90AA1L3MBTL1NPC1KDM4ECCR1
SCHEMBL164214 0.88 L3MBTL1 (0.61) HSP90AA1L3MBTL1NPC1KDM4ECCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195463-A1 ORGANOMETALLIC COMPLEX, CONTROLLED-RELEASE MULTI-FUNCTIONAL DRUG, PHARMACEUTICAL COMPOSITION, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE FACULDADE DE CIENCIAS DA UNIV DE LISBOA (PT) 2025-06-19 US claimed
EP-4508058-A1 ORGANOMETALLIC COMPLEX, CONTROLLED-RELEASE MULTI-FUNCTIONAL DRUG, PHARMACEUTICAL COMPOSITION, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE Faculdade de Ciencias da Universidade de Lisboa (PT) 2025-02-19 EP claimed
WO-2023199134-A1 ORGANOMETALLIC COMPLEX, CONTROLLED-RELEASE MULTI-FUNCTIONAL DRUG, PHARMACEUTICAL COMPOSITION, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-10-19 WO claimed
US-20170145472-A1 METHOD OF DETECTING HELICASE ACTIVITY HONG KONG BAPTIST UNIVERSITY 2017-05-25 US claimed
US-20160101177-A1 pH AND LIGHT ACTIVATED ANTI-CANCER DRUGS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2016-04-14 US claimed
WO-2009080482-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING OCTAHEDRAL METAL (III) POLYPYRIDYL COMPLEXES AND THEIR USE IN PREVENTION AND TREATMENT OF CANCER FREIE UNIVERSITÄT BERLIN (DE) 2009-07-02 WO claimed
EP-2072521-A1 Octahedral metal (III) polypyridyl complexes and their use in prevention and treatment of cancer Freie Universität Berlin (DE) 2009-06-24 EP claimed
US-12545794-B2 Security feature, printing ink, document of value, and manufacturing method GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) 2026-02-10 US disclosed
US-20250195463-A1 ORGANOMETALLIC COMPLEX, CONTROLLED-RELEASE MULTI-FUNCTIONAL DRUG, PHARMACEUTICAL COMPOSITION, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE FACULDADE DE CIENCIAS DA UNIV DE LISBOA (PT) 2025-06-19 US disclosed
WO-2025081785-A1 BINUCLEAR NEUTRAL IRIDIUM COMPLEX, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 江苏科技大学 2025-04-24 WO disclosed
EP-4508058-A1 ORGANOMETALLIC COMPLEX, CONTROLLED-RELEASE MULTI-FUNCTIONAL DRUG, PHARMACEUTICAL COMPOSITION, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE Faculdade de Ciencias da Universidade de Lisboa (PT) 2025-02-19 EP disclosed
US-20250018739-A1 SECURITY FEATURE, PRINTING INK, DOCUMENT OF VALUE, AND MANUFACTURING METHOD GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) 2025-01-16 US disclosed
CN-119119125-A Binuclear neutral iridium complex and preparation method and application thereof 江苏科技大学 2024-12-13 CN disclosed
EP-2072521-A1 Octahedral metal (III) polypyridyl complexes and their use in prevention and treatment of cancer Freie Universität Berlin (DE) 2009-06-24 EP disclosed
EP-2072521-A1 Octahedral metal (III) polypyridyl complexes and their use in prevention and treatment of cancer Freie Universität Berlin (DE) 2009-06-24 EP disclosed
WO-2009067603-A1 PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING BIO-RAD LABORATORIES, INC. (US) 2009-05-28 WO disclosed
US-20090131640-A1 PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING BIO-RAD LABORATORIES, INC. (US) 2009-05-21 US disclosed
US-20090131640-A1 PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING BIO-RAD LABORATORIES, INC. (US) 2009-05-21 US disclosed
CN-101225446-A Method and device for fixing and assembling DNA and markers UNIV SOUTH CHINA NORMAL (CN) 2008-07-23 CN disclosed
US-5646284-A AUTOMOBILE WINDSHIELDS THAT SCREEN LIGHT TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1997-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545794-B2 Security feature, printing ink, document of value, and manufacturing method MRPL9, MRPL19, MRPS9 HSP90AA1 2204/4885L3MBTL1 177/4885NPC1 4127/4885
US-20160101177-A1 pH AND LIGHT ACTIVATED ANTI-CANCER DRUGS CA2, CA6, NFATC1 HSP90AA1 1005/4885L3MBTL1 4448/4885NPC1 4495/4885
US-20090131640-A1 PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING NR2E3, NR2C2, ORC3 HSP90AA1 2633/4885L3MBTL1 822/4885NPC1 3989/4885
US-20250195463-A1 ORGANOMETALLIC COMPLEX, CONTROLLED-RELEASE MULTI-FUNCTIONAL DRUG, PHARMACEUTICAL COMPOSITION, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE SAMM50, CYP4F2, ABCB1 HSP90AA1 2326/4885L3MBTL1 3024/4885NPC1 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.