Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128213 | 1.00 | HSP90AA1 (0.64) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL3070322 | 0.97 | HSP90AA1 (0.61) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL29849953 | 0.97 | HSP90AA1 (0.67) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL4009364 | 0.97 | HSP90AA1 (0.67) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL6045195 | 0.95 | HSP90AA1 (0.58) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL26749762 | 0.94 | HSP90AA1 (0.64) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL18816320 | 0.91 | L3MBTL1 (0.52) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL3305606 | 0.90 | DHFR (0.55) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL4993117 | 0.88 | HSP90AA1 (0.64) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 | |
| SCHEMBL17523388 | 0.88 | HSP90AA1 (0.64) | HSP90AA1L3MBTL1NPC1KDM4ECCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
| US-20160329509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2016-11-10 | — | — | US | disclosed |
| US-20160329509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2016-11-10 | — | — | US | disclosed |
| US-9478758-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-10-25 | — | — | US | disclosed |
| US-9478758-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | HSP90AA1 3267/4885L3MBTL1 206/4885NPC1 3947/4885 |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | HSP90AA1 3424/4885L3MBTL1 24/4885NPC1 3157/4885 |
| US-20160329509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SOD1, SLC25A21, SLC25A11 | HSP90AA1 3163/4885L3MBTL1 1621/4885NPC1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.