Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | TKT | P29401 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934661 | 0.84 | TRPV4 (0.48) | DAOTRPV4TKTKDM1AMAOA | |
| Hydrochloric Acid SCHEMBL4727675 | 0.81 | TRPV4 (0.46) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL13680809 | 0.78 | GRIN1 (0.41) | MRGPRX4GRIN1GRIN2B | |
| SCHEMBL3842669 | 0.78 | KDM1A (0.47) | DAOTRPV4KDM1AMAOAMAOB | |
| SCHEMBL22558739 | 0.78 | L3MBTL1 (0.50) | KCNH2TRPV1 | |
| SCHEMBL264730 | 0.77 | TAAR1 (0.52) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL694114 | 0.77 | DAO (0.50) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL19615786 | 0.77 | TRPV4 (0.53) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL3851699 | 0.77 | DAO (0.50) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL1259004 | 0.77 | TKT (0.55) | DAOTRPV4TKTKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |