Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011470 | 0.88 | FABP3 (0.45) | FABP3FABP4FABP5ADORA3KMT2A | |
| SCHEMBL8027046 | 0.87 | ADORA3 (0.41) | ADORA3KMT2ASMN1; SMN2KDM4EF2 | |
| SCHEMBL4005140 | 0.84 | FABP3 (0.44) | FABP3FABP4FABP5ADORA3KMT2A | |
| SCHEMBL4010068 | 0.83 | PPARG (0.40) | ADORA3KMT2ASMN1; SMN2KDM4EF2 | |
| SCHEMBL4007857 | 0.80 | FABP3 (0.45) | FABP3FABP4FABP5ADORA3KMT2A | |
| SCHEMBL5961069 | 0.79 | FABP3 (0.49) | FABP3FABP4FABP5ADORA3KMT2A | |
| SCHEMBL8030010 | 0.77 | RXRA (0.47) | FABP3FABP4FABP5ADORA3KMT2A | |
| SCHEMBL8033374 | 0.77 | KDM4E (0.50) | FABP3FABP4ADORA3KMT2ASMN1; SMN2 | |
| SCHEMBL4010057 | 0.76 | DPP4 (0.48) | FABP3FABP4FABP5ADORA3KDM4E | |
| SCHEMBL8024870 | 0.75 | GCGR (0.44) | ADORA3KMT2ASMN1; SMN2KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |