Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CTRC | Q99895 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011472 | 0.89 | MAPT (0.39) | PPARGPPARAADORA3MAPTF2 | |
| SCHEMBL4005144 | 0.85 | PPARA (0.39) | PPARGPPARAADORA3MAPTF2 | |
| SCHEMBL4010066 | 0.83 | FABP3 (0.42) | PPARGPPARAADORA3MAPTF2 | |
| SCHEMBL4007862 | 0.81 | NAMPT (0.38) | PPARGPPARAADORA3MAPTF2 | |
| SCHEMBL8027046 | 0.80 | ADORA3 (0.41) | PPARGPPARAADORA3MAPTF2 | |
| SCHEMBL4007725 | 0.78 | ADORA3 (0.39) | ADORA3MAPTF2KMT2ASMN1; SMN2 | |
| SCHEMBL4010060 | 0.78 | DPP4 (0.36) | ADORA3MAPTRAB9ATSHRBCHE | |
| SCHEMBL4008889 | 0.73 | DHPS (0.41) | PPARGPPARAADORA3MAPTSMN1; SMN2 | |
| SCHEMBL4011569 | 0.73 | PDE4B (0.36) | ADORA3MAPTF2KMT2ASMN1; SMN2 | |
| SCHEMBL4008512 | 0.73 | MAPT (0.42) | ADORA3MAPTKMT2ARAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |