Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011470 | 0.88 | FABP3 (0.45) | DPP4DPP8DPP9ADORA3NPC1 | |
| SCHEMBL8038540 | 0.86 | GCGR (0.45) | DPP4DPP8DPP9ADORA3ADORA1 | |
| SCHEMBL4011133 | 0.85 | LDHA (0.41) | DPP4DPP8DPP9ADORA3HTT | |
| SCHEMBL4010060 | 0.81 | DPP4 (0.36) | DPP4DPP8DPP9ADORA3ADORA1 | |
| SCHEMBL4009023 | 0.81 | DPP4 (0.42) | DPP4DPP8DPP9ADORA3ADORA1 | |
| SCHEMBL4009387 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9ADORA3ADORA1 | |
| SCHEMBL4011273 | 0.77 | ADORA3 (0.38) | DPP4DPP8DPP9ADORA3ADORA1 | |
| SCHEMBL4005140 | 0.76 | FABP3 (0.44) | ADORA3NPC1RAB9ANPSR1LMNA | |
| SCHEMBL4010066 | 0.76 | FABP3 (0.42) | ADORA3NPC1RAB9ANPSR1POLB | |
| SCHEMBL8024870 | 0.74 | GCGR (0.44) | ADORA3NPC1RAB9ANPSR1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |