Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988281 | 0.84 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL49366 | 0.84 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL10592307 | 0.82 | LTA4H (0.58) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL8720652 | 0.77 | LTA4H (0.58) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL16890420 | 0.77 | LTA4H (0.58) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL4016558 | 0.75 | LTA4H (0.50) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL28177362 | 0.75 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL30967442 | 0.75 | ALOX15 (0.56) | ALOX15ALOX12AKR1B1LTA4HNR1H2 | |
| SCHEMBL6743011 | 0.73 | LTA4H (0.42) | LTA4HNR1H2BAXTSHRKDM4E | |
| SCHEMBL10765394 | 0.72 | MEN1 (0.54) | ALOX15ALOX12AKR1B1LTA4HNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083030-A1 | METHOD FOR PREDICTING A TOXIC EFFECT OF A COMPOUND | VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS (NL) | 2009-07-09 | — | — | WO | disclosed |