SCHEMBL49366

SCHEMBL49366

Brc1c(Br)c(Br)c(Oc2ccccc2)c(Br)c1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.55
TSHR P16473 1/20 0.55
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
MAPT P10636 1/20 0.46
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42
MAOA P21397 1/20 0.42
GSTP1 P09211 1/20 0.40
SOS1 Q07889 1/20 0.40
CA9 Q16790 1/20 0.40
PARP10 Q53GL7 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10592307 0.97 LTA4H (0.58) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL9988281 0.95 LTA4H (0.55) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL16890420 0.86 LTA4H (0.58) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL4010724 0.84 ALOX15 (0.49) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL4016558 0.84 LTA4H (0.50) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL6743011 0.83 LTA4H (0.42) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL17273646 0.80 LTA4H (0.73) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL11678987 0.80 LTA4H (0.41) LTA4HTSHRKMT2AKDM4EGLA
SCHEMBL29982280 0.79 MAPT (0.52) LTA4HTSHRKMT2AMAPTCA1
SCHEMBL21969982 0.77 LTA4H (0.46) LTA4HTSHRKMT2AKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2733 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346506-A1 Membrane-Mediated Electro-Oxidation-Reduction Deep Water Treatment Device and its Operation Method Thereof HARBIN INST TECHNOLOGY (CN) 2025-11-13 US claimed
CN-119780313-A Determination method of polybrominated diphenyl ether substances 盐城工学院 2025-04-08 CN claimed
CN-119708308-A High-melt-index high-Vicat polystyrene resin, and preparation method and application thereof 常州瑞华化工工程技术股份有限公司 2025-03-28 CN claimed
WO-2025062099-A2 PREPARATION OF POLYSTYRENE USING 1,3 1,4 BIS(TERT-ALKYLPEROXYDIISOPROPYL)BENZENES ARKEMA FRANCE (FR) 2025-03-27 WO claimed
WO-2025062100-A2 PREPARATION OF POLYSTYRENE USING 1,3 1,4 BIS(TERT-ALKYLPEROXYDIISOPROPYL)BENZENES ARKEMA FRANCE (FR) 2025-03-27 WO claimed
CN-116239849-B Aging-resistant rubber material for rubber lining pipeline and preparation method thereof 张家口市华跃防腐耐磨管道有限公司 2025-01-24 CN claimed
US-20240391811-A1 SYSTEM AND METHOD FOR CONTINUOUS METABOLISM OF CONTAMINANTS OF EMERGING CONCERN The Florida State University Research Foundation, Inc. 2024-11-28 US claimed
CN-118562289-B Preparation method of material of full-plastic carrier roller bracket for coal mine transportation and carrier roller bracket 西安重装蒲白煤矿机械有限公司 2024-11-08 CN claimed
CN-118562289-A Preparation method of material of full-plastic carrier roller bracket for coal mine transportation and carrier roller bracket 西安重装蒲白煤矿机械有限公司 2024-08-30 CN claimed
CN-118388905-A Fluororubber composite material with high acid resistance for plate heat exchanger and preparation method 中绿新材料(江苏)有限公司 2024-07-26 CN claimed
US-4278767-A Fire-retardant monocarboxylic acid copolymers ARCO POLYMERS, INC. (US) 1981-07-14 US claimed
US-4271271-A Fire-retardant monocarboxlylic acid amide copolymers ARCO POLYMERS, INC. (US) 1981-06-02 US claimed
US-4266037-A Fire-retardant imide copolymers ARCO POLYMERS, INC. (US) 1981-05-05 US claimed
US-4266038-A Rubber-modified fire-retardant imide copolymers ARCO POLYMERS, INC. (US) 1981-05-05 US claimed
US-4214103-A BY TREATMENT WITH A POWDER OF A BASE GREAT LAKES CHEMICAL CORPORATION (US) 1980-07-22 US claimed
US-4203882-A AUTOMOBILE BUMPERS MONTEDISON S.P.A. (IT) 1980-05-20 US claimed
US-4178408-A CONDENSED EPOXY COMPOUND AND PENTABROMODIPHENYL ETHER DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-12-11 US claimed
US-4117027-A WATER RESISTANT RAYCHEM CORPORATION (US) 1978-09-26 US claimed
US-4074015-A Process for the production of nonflammable laminated materials DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-02-14 US claimed
US-4056656-A PHENOLIC RESIN, PENTABROMODIPHENYL ETHER, PLASTICIZER DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed