Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962553 | 0.91 | ENPP2 (0.35) | ENPP2PRMT5WDR77GPBAR1TAAR1 | |
| SCHEMBL4012388 | 0.89 | PTGDR2 (0.38) | ENPP2GPBAR1GRM2PTGDR2 | |
| SCHEMBL13962989 | 0.85 | ENPP2 (0.36) | ENPP2GPBAR1TAAR1MAPK1PTGDR2 | |
| SCHEMBL4010973 | 0.83 | ENPP2 (0.41) | ENPP2TAAR1MAPK1PTGDR2 | |
| SCHEMBL13962556 | 0.82 | GPBAR1 (0.45) | ENPP2GPBAR1TAAR1PTGDR2 | |
| SCHEMBL4015287 | 0.80 | TRPV1 (0.39) | — | |
| SCHEMBL4009139 | 0.79 | PTGDR2 (0.36) | GPBAR1PTGDR2 | |
| SCHEMBL4015621 | 0.78 | TIPARP (0.37) | ENPP2GPBAR1TAAR1 | |
| SCHEMBL4012243 | 0.77 | GPBAR1 (0.50) | GPBAR1PTGDR2 | |
| SCHEMBL13962993 | 0.76 | GPBAR1 (0.44) | ENPP2GPBAR1KCNK3PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |