Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115838 | 0.89 | CTSL (0.58) | SIRT5CTSLMMP3 | |
| SCHEMBL27987607 | 0.89 | CTSL (0.58) | SIRT5CTSLMMP3 | |
| SCHEMBL4011349 | 0.88 | F2 (0.64) | HDAC8CTSLF2PRSS1PRSS2 | |
| SCHEMBL22034417 | 0.88 | SIRT5 (0.69) | SIRT5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22034415 | 0.88 | SIRT5 (0.69) | SIRT5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1674876 | 0.87 | SSTR3 (0.64) | SIRT5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22034624 | 0.85 | SIRT5 (0.61) | SIRT5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22034622 | 0.85 | SIRT5 (0.61) | SIRT5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5348200 | 0.84 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29897716 | 0.84 | SIRT1 (0.60) | SIRT5SIRT1SIRT2CTSLF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601005-B1 | DETERGENT ENZYMES | NOVO NORDISK AS (DK) | 2000-11-22 | — | — | EP | disclosed |
| EP-0579710-B1 | NOVEL PROTEASES FROM DENDRYPHIELLA | NOVO NORDISK AS (DK) | 1997-12-29 | — | — | EP | disclosed |
| US-5472865-A | Protease from Dendryphiella arenaria DSM 6260 or Dendryphiella salina DSM 6332, process for making it and use as detergent additive | NOVO NORDISK A/S (DK) | 1995-12-05 | — | — | US | disclosed |
| EP-0601005-A1 | DETERGENT ENZYMES | NOVO NORDISK A/S (DK) | 1994-06-15 | — | — | EP | disclosed |
| EP-0579710-A1 | NOVEL PROTEASES FROM DENDRYPHIELLA | NOVO NORDISK A/S (DK) | 1994-01-26 | — | — | EP | disclosed |
| WO-1993004156-A1 | DETERGENT ENZYMES | NOVO NORDISK A/S (DK) | 1993-03-04 | — | — | WO | disclosed |
| WO-1992018622-A1 | NOVEL PROTEASES | NOVO NORDISK A/S (DK) | 1992-10-29 | — | — | WO | disclosed |