Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376873 | 0.76 | HTR1A (0.35) | HTR2AHTR2CHTR2BSIGMAR1LMNA | |
| SCHEMBL10446610 | 0.75 | SIGMAR1 (0.42) | HTR2AHTR2CHTR2BSIGMAR1KDM1A | |
| SCHEMBL7346477 | 0.74 | KDM1A (0.38) | KDM1ALMNATDP1 | |
| SCHEMBL6071126 | 0.72 | GAA (0.40) | LMNATDP1 | |
| SCHEMBL9515103 | 0.70 | SIGMAR1 (0.43) | HTR2AHTR2CHTR2BSIGMAR1KDM1A | |
| SCHEMBL7351257 | 0.70 | KMT2A (0.40) | LMNA | |
| SCHEMBL28268454 | 0.70 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1KDM1A | |
| SCHEMBL28266737 | 0.70 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1KDM1A | |
| SCHEMBL7852382 | 0.69 | MAPK1 (0.46) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7852383 | 0.69 | MAPK1 (0.46) | HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012376-A1 | COMPOSITIONS AND METHODS FOR SKIN CARE | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-01-22 | — | — | WO | disclosed |