⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364803 | 0.77 | — | — | |
| SCHEMBL16728888 | 0.70 | GPR3 (0.39) | — | |
| SCHEMBL20027221 | 0.70 | GPR3 (0.39) | — | |
| SCHEMBL11527828 | 0.64 | NISCH (0.40) | — | |
| SCHEMBL2885054 | 0.63 | — | — | |
| SCHEMBL3269797 | 0.62 | KDM4E (0.40) | — | |
| SCHEMBL1398558 | 0.62 | NOTUM (0.39) | — | |
| SCHEMBL10967597 | 0.62 | — | — | |
| SCHEMBL20482181 | 0.60 | BRD4 (0.41) | — | |
| SCHEMBL1398556 | 0.60 | CYP11B2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569562-B2 | N-substituted heterocyclic sulfonamides | ELAN PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| EP-1838701-A1 | N-SUBSTITUTED HETEROCYCLIC SULFONAMIDES | Elan Pharmaceuticals Inc. (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20060270657-A1 | N-substituted heterocyclic sulfonamides | ELAN PHARMACEUTICALS, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2006078753-A1 | N-SUBSTITUTED HETEROCYCLIC SULFONAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | WO | disclosed |