Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 18/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13963132 | 0.88 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL4012387 | 0.80 | ENPP2 (0.35) | — | |
| SCHEMBL13962556 | 0.79 | GPBAR1 (0.45) | — | |
| SCHEMBL3100584 | 0.78 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL3100577 | 0.78 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL3936207 | 0.76 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL4009139 | 0.76 | PTGDR2 (0.36) | — | |
| SCHEMBL4013236 | 0.75 | PTGDR2 (0.34) | — | |
| SCHEMBL4012243 | 0.74 | GPBAR1 (0.50) | — | |
| SCHEMBL4012024 | 0.74 | SMN1; SMN2 (0.40) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |