Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ME2 | P23368 | 2/20 | 0.38 |
| ▸ | ME1 | P48163 | 2/20 | 0.38 |
| ▸ | ME3 | Q16798 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PRLHR | P49683 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962556 | 0.94 | GPBAR1 (0.45) | GPBAR1PTGDR2 | |
| SCHEMBL13962993 | 0.88 | GPBAR1 (0.44) | GPBAR1PTGDR2 | |
| SCHEMBL4007085 | 0.83 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL31018181 | 0.82 | L3MBTL1 (0.40) | PRLHRPTGDR2 | |
| SCHEMBL21612764 | 0.82 | L3MBTL1 (0.40) | PRLHRPTGDR2 | |
| SCHEMBL21615973 | 0.81 | KMT2A (0.41) | GPBAR1PRLHR | |
| SCHEMBL31018186 | 0.78 | TRPV1 (0.39) | PRLHRPTGDR2 | |
| SCHEMBL3099388 | 0.78 | TRPV1 (0.39) | PRLHRPTGDR2 | |
| SCHEMBL3099369 | 0.78 | TRPV1 (0.39) | PRLHRPTGDR2 | |
| SCHEMBL4012387 | 0.77 | ENPP2 (0.35) | GPBAR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |