Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014998 | 0.88 | FAAH (0.70) | FAAHMAPTEPHX2ALPLKDM4E | |
| SCHEMBL4007889 | 0.84 | FAAH (0.67) | FAAHLMNAEPHX2ALPLKDM4E | |
| SCHEMBL3929062 | 0.84 | FAAH (0.75) | FAAHLMNAALPLSMN1; SMN2 | |
| SCHEMBL4011830 | 0.83 | FAAH (0.65) | FAAHLMNAEPHX2ALPLKDM4E | |
| SCHEMBL3931338 | 0.83 | FAAH (0.79) | FAAHLMNAEPHX2ALPLHTR6 | |
| SCHEMBL4016142 | 0.82 | FAAH (0.67) | FAAHLMNAEPHX2ALPLKDM4E | |
| SCHEMBL3936894 | 0.82 | FAAH (0.79) | FAAHLMNAEPHX2ALPLKDM4E | |
| SCHEMBL3931443 | 0.82 | FAAH (0.77) | FAAHLMNAEPHX2ALPLKDM4E | |
| SCHEMBL3931235 | 0.82 | FAAH (0.69) | FAAHLMNAALPLKDM4EALDH1A1 | |
| SCHEMBL3941303 | 0.82 | FAAH (0.82) | FAAHALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |