Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PRLHR | P49683 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016104 | 0.79 | AGBL2 (0.41) | ALDH1A1 | |
| SCHEMBL4008304 | 0.78 | GAA (0.36) | PTGDR2ALDH1A1PRLHR | |
| SCHEMBL4009139 | 0.77 | PTGDR2 (0.36) | PTGDR2GPBAR1ALDH1A1PRLHR | |
| SCHEMBL13962556 | 0.76 | GPBAR1 (0.45) | PTGDR2GPBAR1ENPP2TAAR1 | |
| SCHEMBL4015621 | 0.76 | TIPARP (0.37) | GPBAR1ALDH1A1ENPP2TAAR1PRLHR | |
| SCHEMBL4011125 | 0.76 | ALDH1A1 (0.37) | PTGDR2GPBAR1ALDH1A1 | |
| SCHEMBL4012024 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1 | |
| SCHEMBL4012387 | 0.76 | ENPP2 (0.35) | PTGDR2GPBAR1GRM2MAPK1ENPP2 | |
| SCHEMBL13962555 | 0.76 | MAPT (0.43) | ALDH1A1 | |
| SCHEMBL4015104 | 0.75 | PTGDR2 (0.39) | PTGDR2GPBAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |