Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531232 | 0.88 | LMNA (0.45) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL9510197 | 0.81 | ALDH1A1 (0.40) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL27741276 | 0.79 | ALDH1A1 (0.43) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL8784684 | 0.76 | METAP2 (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL7892110 | 0.76 | LMNA (0.43) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL11923661 | 0.76 | LMNA (0.43) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL7880901 | 0.76 | LMNA (0.43) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL7892540 | 0.76 | LMNA (0.43) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL27761827 | 0.76 | ALDH1A1 (0.44) | HTTKMT2AMEN1LMNAPOLB | |
| SCHEMBL7888501 | 0.76 | LMNA (0.43) | HTTKMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |