Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326384 | 0.83 | MAPT (0.43) | MAPTADORA2BXDHENPP1ACHE | |
| SCHEMBL7326964 | 0.78 | MAPT (0.42) | MAPTADORA2BXDHENPP1ACHE | |
| SCHEMBL60159 | 0.78 | TSHR (0.46) | MAPTADORA2BXDHENPP1ACHE | |
| SCHEMBL380136 | 0.75 | MAPT (0.48) | MAPTADORA2BXDHACHEGDA | |
| SCHEMBL31438586 | 0.75 | MAPT (0.48) | MAPTADORA2BXDHENPP1ACHE | |
| SCHEMBL8700368 | 0.75 | MAPT (0.42) | MAPTADORA2BXDHENPP1ACHE | |
| SCHEMBL541696 | 0.75 | MAPT (0.42) | MAPTADORA2BXDHACHEGDA | |
| SCHEMBL3489066 | 0.74 | HCAR2 (0.42) | MAPTADORA2BXDHENPP1ACHE | |
| SCHEMBL6268082 | 0.74 | PNP (0.53) | MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL31265613 | 0.73 | MAPT (0.40) | MAPTADORA2BXDHENPP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146229-A | Preparation method of nanofiber scaffold and method for constructing tissue engineering material by adopting nanofiber scaffold and melanocytes | 上海麦野生物科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| US-20090148546-A1 | Methods and compounds fo rthe treatment of obesity and obesity-related disorders | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2009-06-11 | — | — | US | disclosed |
| US-7479540-B1 | Adipomodulin and related molecules and methods | PRASAD CHANDAN | 2009-01-20 | — | — | US | disclosed |
| WO-2006086764-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS | THE BOARD OF SUPERVISOR OF LOUISIANA STATE UNIVERSITY AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20060182825-A1 | Methods and compounds for the treatment of obesity and obesity-related disorders | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2006-08-17 | — | — | US | disclosed |