Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326392 | 0.84 | PNP (0.49) | PNPALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL7326970 | 0.80 | PNP (0.48) | PNPALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL60160 | 0.80 | PNP (0.47) | PNPALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL380137 | 0.77 | PNP (0.50) | PNPALDH1A1KMT2ASMN1; SMN2TK1 | |
| SCHEMBL8884657 | 0.77 | PNP (0.51) | PNPALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9386892 | 0.77 | PNP (0.47) | PNPALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7217325 | 0.76 | PNP (0.49) | PNPALDH1A1KMT2ASMN1; SMN2TK1 | |
| SCHEMBL3489068 | 0.76 | PNP (0.44) | PNPALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3688591 | 0.76 | SMN1; SMN2 (0.50) | PNPALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5054173 | 0.75 | PNP (0.54) | PNPALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146229-A | Preparation method of nanofiber scaffold and method for constructing tissue engineering material by adopting nanofiber scaffold and melanocytes | 上海麦野生物科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| US-20090148546-A1 | Methods and compounds fo rthe treatment of obesity and obesity-related disorders | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2009-06-11 | — | — | US | disclosed |
| US-7479540-B1 | Adipomodulin and related molecules and methods | PRASAD CHANDAN | 2009-01-20 | — | — | US | disclosed |
| WO-2006086764-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS | THE BOARD OF SUPERVISOR OF LOUISIANA STATE UNIVERSITY AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20060182825-A1 | Methods and compounds for the treatment of obesity and obesity-related disorders | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2006-08-17 | — | — | US | disclosed |