SCHEMBL667985

SCHEMBL667985

[c]1c(-c2ccccc2)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 5/20 0.38
RAB9A P51151 2/20 0.38
MAOB P27338 1/20 0.38
PTGS2 P35354 1/20 0.37
BACE1 P56817 1/20 0.37
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
MPI P34949 1/20 0.36
GPR84 Q9NQS5 3/20 0.35
ADORA3 P0DMS8 2/20 0.34
ADORA2A P29274 2/20 0.34
ADORA1 P30542 2/20 0.34
FGFR1 P11362 1/20 0.34
SRC P12931 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PSMB5 P28074 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4808028 0.85 MEN1 (0.45) ALDH1A1KDM4ERAB9AMAOBPTGS2
SCHEMBL6400913 0.85 ESR2 (0.44) ALDH1A1KDM4ERAB9AMEN1KMT2A
SCHEMBL67310 0.85 PTGS2 (0.39) ALDH1A1KDM4ERAB9AMAOBPTGS2
SCHEMBL668633 0.83 ALDH1A1 (0.40) ALDH1A1KDM4EMAOBMEN1KMT2A
SCHEMBL669474 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL11837610 0.83 CYP2A6 (0.50) ALDH1A1KDM4ERAB9AMAOBPTGS2
SCHEMBL5887304 0.81 ABL1 (0.47) ALDH1A1KDM4ERAB9ABACE1MEN1
SCHEMBL4014642 0.79 GSTP1 (0.48) ALDH1A1KDM4ERAB9AHPGDMAPT
SCHEMBL1234940 0.79 ALDH1A1 (0.37) ALDH1A1HPGDL3MBTL1ATMHSD17B10
SCHEMBL5887233 0.79 LTA4H (0.49) ALDH1A1KDM4ERAB9ABACE1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685562-A Diphenyl naphthyl phosphine oxide derivative with asymmetric structure, organic electron transport material, preparation and application thereof 华南理工大学 2022-07-01 CN claimed
CN-113563316-A Aromatic amine derivative and application thereof 江苏三月科技股份有限公司 2021-10-29 CN claimed
US-5646144-A FOR TREATING DISORDERS IN WHICH SUBSTANCE P PLAYS A PART IN DEVELOPMENT CIBA-GEIGY CORPORATION (US) 1997-07-08 US claimed
CN-113563316-B Aromatic amine derivative and application thereof 江苏三月科技股份有限公司 2024-07-05 CN disclosed
WO-2024135665-A1 POLYIMIDE COMPOUND, NEGATIVE ELECTRODE MATERIAL FOR LITHIUM ION SECONDARY BATTERIES THAT USES SAID POLYIMIDE COMPOUND, NEGATIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERIES, AND LITHIUM ION SECONDARY BATTERY ウィンゴーテクノロジー株式会社 2024-06-27 WO disclosed
EP-4318676-A1 POLYIMIDE COMPOUND, NEGATIVE ELECTRODE MATERIAL FOR LITHIUM ION SECONDARY BATTERIES THAT USES SAID POLYIMIDE COMPOUND, NEGATIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERIES, AND LITHIUM ION SECONDARY BATTERY Wingo Technology Co., Ltd. (JP) 2024-02-07 EP disclosed
CN-117043991-A Polyimide compound, negative electrode material for lithium ion secondary battery using same, negative electrode for lithium ion secondary battery, and lithium ion secondary battery 胜高科技股份有限公司 2023-11-10 CN disclosed
CN-111770951-B Polyimide compound and molded article comprising same 胜高科技股份有限公司 2023-04-11 CN disclosed
CN-114685562-A Diphenyl naphthyl phosphine oxide derivative with asymmetric structure, organic electron transport material, preparation and application thereof 华南理工大学 2022-07-01 CN disclosed
US-20220162445-A1 POLYIMIDE COMPOUND AND MOLDED ARTICLE COMPRISING THE POLYIMIDE COMPOUND WINGO TECHNOLOGY CO., LTD. (JP) 2022-05-26 US disclosed
EP-3919548-A1 POLYIMIDE COMPOUND AND MOLDED ARTICLE CONTAINING SAID POLYIMIDE COMPOUND Wingo Technology Co., Ltd. (JP) 2021-12-08 EP disclosed
CN-1645977-A Organic electroluminescent display device and method of manufacturing the same HITACHI DISPLAYS LTD (JP) 2005-07-27 CN disclosed
WO-2004076421-A1 HETEROCYCLIC AMIDES, METHOD FOR THE PRODUCTION THEREOF, SUBSTANCES CONTAINING SAID HETEROCYCLIC AMIDES, AND USE THEREOF AS PESTICIDES BAYER CROPSCIENCE GMBH (DE) 2004-09-10 WO disclosed
EP-1434485-A1 NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES SERVING AS PESTICIDES Bayer CropScience GmbH (DE) 2004-07-07 EP disclosed
US-20040006047-A1 Heterocyclic amides, a process for their preparation, compositions comprising them and their use MERIAL LIMITED 2004-01-08 US disclosed
WO-2003028459-A1 NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES SERVING AS PESTICIDES BAYER CROPSCIENCE GMBH (DE) 2003-04-10 WO disclosed
EP-1214630-A2 MICROFABRICATED DEVICES AND METHOD OF MANUFACTURING THE SAME THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2002-06-19 EP disclosed
WO-2001007506-A2 MICROFABRICATED DEVICES AND METHOD OF MANUFACTURING THE SAME THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2001-02-01 WO disclosed
US-5260451-A Enzyme inhibitors MERCKLE GMBH (DE) 1993-11-09 US disclosed
US-4813974-A Removal of excess halide ions in aqueous liquid formulations of basic dyestuffs MOBAY CORPORATION (US) 1989-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006047-A1 Heterocyclic amides, a process for their preparation, compositions comprising them and their use CBR1, HCN1, SCN1A ALDH1A1 1221/4885KDM4E 1596/4885RAB9A 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.