Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888425 | 0.85 | TAAR1 (0.53) | ALOX15ALOX12TSHRKIF11CYP1A2 | |
| SCHEMBL9588776 | 0.82 | ALOX15 (0.53) | ALOX15ALOX12TSHRKIF11SMN1; SMN2 | |
| SCHEMBL10769004 | 0.80 | KIF11 (0.41) | ALOX15ALOX12KIF11CYP2A6TAAR1 | |
| SCHEMBL28231963 | 0.80 | ALOX15 (0.51) | ALOX15ALOX12TSHRKIF11SMN1; SMN2 | |
| SCHEMBL3755915 | 0.80 | CTNNB1 (0.41) | KIF11NPC1RAB9ACYP2A6LOXL2 | |
| SCHEMBL25084169 | 0.80 | ALOX15 (0.55) | ALOX15ALOX12TSHRKIF11SMN1; SMN2 | |
| SCHEMBL31139932 | 0.80 | CTNNB1 (0.41) | KIF11NPC1RAB9ACYP2A6LOXL2 | |
| SCHEMBL11630777 | 0.80 | ALOX15 (0.51) | ALOX15ALOX12TSHRKIF11SMN1; SMN2 | |
| SCHEMBL31009079 | 0.80 | ALOX15 (0.55) | ALOX15ALOX12TSHRKIF11SMN1; SMN2 | |
| SCHEMBL2472068 | 0.79 | PDPK1 (0.37) | ALOX15ALOX12TSHRKIF11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178547-A1 | BENZOXAZINE POLYMERS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |
| CN-1993323-B | Indole, indazole or indoline derivatives | HOFFMANN LA ROCHE | 2011-04-20 | — | — | CN | disclosed |
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | KOTNIK MIHA | 2009-10-01 | — | — | US | disclosed |
| EP-2074124-A1 | 3- (BENZO [D][1,3]DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | Lek Pharmaceuticals D.D. (SI) | 2009-07-01 | — | — | EP | disclosed |
| EP-1916249-A1 | 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents | LEK Pharmaceuticals D.D. (SI) | 2008-04-30 | — | — | EP | disclosed |
| WO-2008043733-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | LEK PHARMACEUTICAL D.D. (SI) | 2008-04-17 | — | — | WO | disclosed |
| CN-1993323-A | Indole, indazole or indoline derivatives | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | XDH, TXLNA, Q6ZSR9 | ALOX15 3078/4885ALOX12 2191/4885TSHR 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.