Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25505996 | 0.84 | ALOX15 (0.40) | ALOX15ALOX12TSHRPARP1TRPA1 | |
| SCHEMBL9589157 | 0.84 | ALOX15 (0.50) | ALOX15ALOX12TSHRTRPA1CYP1A2 | |
| SCHEMBL31009079 | 0.82 | ALOX15 (0.55) | ALOX15ALOX12TSHRCYP1A2HPGD | |
| SCHEMBL4014702 | 0.82 | ALOX15 (0.51) | ALOX15ALOX12TSHRCYP1A2HPGD | |
| SCHEMBL28231963 | 0.82 | ALOX15 (0.51) | ALOX15ALOX12TSHRCYP1A2HPGD | |
| SCHEMBL25084169 | 0.82 | ALOX15 (0.55) | ALOX15ALOX12TSHRCYP1A2HPGD | |
| SCHEMBL2663369 | 0.82 | CTNNB1 (0.41) | ALOX15ALOX12PARP1TRPA1NPC1 | |
| SCHEMBL11630777 | 0.82 | ALOX15 (0.51) | ALOX15ALOX12TSHRTRPA1CYP1A2 | |
| SCHEMBL10921758 | 0.82 | PARP1 (0.40) | ALOX15ALOX12TSHRPARP1TRPA1 | |
| SCHEMBL2663547 | 0.82 | PARP1 (0.40) | ALOX15ALOX12PARP1TRPA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178547-A1 | BENZOXAZINE POLYMERS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |
| US-10414864-B2 | Degradable amino acid-based poly (ester urea) copolymer adhesives | THE UNIVERSITY OF AKRON (US) | 2019-09-17 | — | — | US | disclosed |
| US-10336862-B2 | Biodegradable polymers with pendant functional groups attached through amide bonds | THE UNIVERSITY OF AKRON (US) | 2019-07-02 | — | — | US | disclosed |
| US-10308595-B2 | Albicidin derivatives, their use and synthesis | Technische Universität Berlin (DE) | 2019-06-04 | — | — | US | disclosed |
| US-20170247506-A1 | BIODEGRADABLE POLYMERS WITH PENDANT FUNCTIONAL GROUPS ATTACHED THROUGH AMIDE BONDS | THE UNIVERSITY OF AKRON | 2017-08-31 | — | — | US | disclosed |
| US-20170247506-A1 | BIODEGRADABLE POLYMERS WITH PENDANT FUNCTIONAL GROUPS ATTACHED THROUGH AMIDE BONDS | THE UNIVERSITY OF AKRON | 2017-08-31 | — | — | US | disclosed |
| US-20170210852-A1 | DEGRADABLE AMINO ACID-BASED POLY (ESTER UREA) COPOLYMER ADHESIVES | THE UNIVERSITY OF AKRON (US) | 2017-07-27 | — | — | US | disclosed |
| US-9593201-B2 | Biodegradable polymers with pendant functional groups attached through amide bonds | THE UNIVERSITY OF AKRON (US) | 2017-03-14 | — | — | US | disclosed |
| US-20120322798-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-20 | — | — | US | disclosed |
| US-8318733-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-11-27 | — | — | US | disclosed |
| US-20100210638-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-08-19 | — | — | US | disclosed |
| US-7741321-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-06-22 | — | — | US | disclosed |
| US-20090143381-A1 | MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2009-06-04 | — | — | US | disclosed |
| US-20080306062-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2008-12-11 | — | — | US | disclosed |
| US-20080113985-A1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED | 2008-05-15 | — | — | US | disclosed |
| US-5214034-A | Improved secretion of nerve growth factor | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5102906-A | Alzheimer*s disease | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0261977-B1 | CATECHOL DERIVATIVES, AND PREVENTIVE AND REMEDIAL PREPARATIONS FOR REGRESSIVE DISORDERS IN THE CENTRAL NERVOUS SYSTEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4985458-A | TREATMENT OF ALZHEIMER*S DISEASE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0261977-A2 | Catechol derivatives, and preventive and remedial preparations for regressive disorders in the central nervous system | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308595-B2 | Albicidin derivatives, their use and synthesis | MB, ALB, BCAT2 | ALOX15 2944/4885ALOX12 2894/4885TSHR 3877/4885 |
| US-20170210852-A1 | DEGRADABLE AMINO ACID-BASED POLY (ESTER UREA) COPOLYMER ADHESIVES | PNMT, UBE3A, PCNA | ALOX15 1616/4885ALOX12 1505/4885TSHR 4612/4885 |
| US-20120322798-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | ALOX15 3135/4885ALOX12 3082/4885TSHR 3010/4885 |
| US-20080113985-A1 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | ALOX15 2798/4885ALOX12 2705/4885TSHR 2723/4885 |
| US-20100210638-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALOX15 2798/4885ALOX12 2705/4885TSHR 2723/4885 |
| US-20080306062-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALOX15 2798/4885ALOX12 2705/4885TSHR 2723/4885 |
| US-20090143381-A1 | MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALOX15 2962/4885ALOX12 2902/4885TSHR 2724/4885 |
| US-10414864-B2 | Degradable amino acid-based poly (ester urea) copolymer adhesives | PNMT, UBE3A, PCNA | ALOX15 1616/4885ALOX12 1505/4885TSHR 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.