Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRLHR | P49683 | 3/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008304 | 0.91 | GAA (0.36) | PTGDR2NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL4014897 | 0.84 | NPSR1 (0.47) | PTGDR2NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL13963195 | 0.84 | NPSR1 (0.40) | PTGDR2NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL4010032 | 0.82 | PRLHR (0.38) | PTGDR2NPSR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL4004746 | 0.76 | PTGDR2 (0.45) | PTGDR2NPSR1MAPTHTTKDM4E | |
| SCHEMBL4012388 | 0.76 | PTGDR2 (0.38) | PTGDR2NPSR1MAPTHTTHPGD | |
| SCHEMBL4011125 | 0.75 | ALDH1A1 (0.37) | PTGDR2NPSR1ALDH1A1MAPTKDM4E | |
| SCHEMBL4016104 | 0.74 | AGBL2 (0.41) | NPSR1ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL4012990 | 0.74 | TRPV4 (0.40) | PTGDR2NPSR1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4012751 | 0.73 | PTGDR2 (0.40) | PTGDR2NPSR1MAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |