Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009251 | 0.87 | HSD11B1 (0.43) | MMP2HSD11B1FFAR1MMP13KEAP1 | |
| SCHEMBL4011688 | 0.83 | PTGDR2 (0.43) | HSD11B1CA12CA2SMN1; SMN2CA9 | |
| SCHEMBL1866007 | 0.81 | PTPN11 (0.38) | MMP2MMP12HSD11B1MMP13MMP1 | |
| SCHEMBL4014555 | 0.78 | KMT2A (0.44) | MMP2MMP12FFAR1MMP13KEAP1 | |
| SCHEMBL20183917 | 0.78 | LMNA (0.56) | RAB9ASMN1; SMN2 | |
| SCHEMBL2181909 | 0.75 | ENPP2 (0.47) | MMP2MMP12 | |
| SCHEMBL11326000 | 0.73 | KEAP1 (0.57) | HSD11B1KEAP1NFE2L2TAS2R14CA12 | |
| SCHEMBL6425280 | 0.73 | HSD11B1 (0.69) | HSD11B1KEAP1NFE2L2TSHRCA12 | |
| SCHEMBL4008150 | 0.72 | HDAC4 (0.36) | MMP2MMP12MMP13MMP3MMP1 | |
| SCHEMBL1829727 | 0.72 | HSD11B1 (0.49) | MMP2HSD11B1MMP13MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |