Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321012 | 0.89 | CYP3A4 (0.42) | SMN1; SMN2HPGDRAB9ANPC1L3MBTL1 | |
| SCHEMBL3145602 | 0.84 | CYP3A4 (0.40) | SMN1; SMN2HPGDRAB9ANPC1POLB | |
| SCHEMBL2539193 | 0.84 | MAPT (0.44) | SMN1; SMN2HPGDL3MBTL1POLBCYP3A4 | |
| SCHEMBL11636131 | 0.83 | MAPT (0.50) | SMN1; SMN2HPGDRAB9ANPC1CYP3A4 | |
| SCHEMBL14320957 | 0.82 | LIPG (0.51) | SMN1; SMN2LIPGMAPTHSD17B10 | |
| SCHEMBL11380769 | 0.82 | LIPG (0.51) | SMN1; SMN2LIPGMAPTHSD17B10 | |
| SCHEMBL14785273 | 0.80 | CYP3A4 (0.46) | SMN1; SMN2RAB9APOLBCYP3A4CYP2D6 | |
| SCHEMBL14191957 | 0.79 | TDP1 (0.47) | SMN1; SMN2L3MBTL1POLBCYP3A4GAA | |
| SCHEMBL31390779 | 0.79 | TDP1 (0.47) | SMN1; SMN2L3MBTL1POLBCYP3A4GAA | |
| SCHEMBL9754655 | 0.79 | KCNH3 (0.49) | SMN1; SMN2CYP2D6CYP2C9GAALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091095-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC LIGHT EMITTING LAYER AND DIODE COMPRISING THE SAME | DOOSAN CORPORATION (KR) | 2009-07-23 | — | — | WO | disclosed |