Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DDX3X | O00571 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321012 | 0.95 | CYP3A4 (0.42) | CYP3A4CYP2D6CYP2C9LIPGPOLB | |
| SCHEMBL2539193 | 0.89 | MAPT (0.44) | CYP3A4CYP2D6CYP2C9LIPGPOLB | |
| SCHEMBL3142020 | 0.89 | ADRA2B (0.40) | CYP2D6CYP2C9MAPTGAATDP1 | |
| SCHEMBL11636131 | 0.88 | MAPT (0.50) | CYP3A4CYP2D6CYP2C9LIPGMAPT | |
| SCHEMBL14320957 | 0.88 | LIPG (0.51) | LIPGMAPTSMN1; SMN2HSD17B10KCNH3 | |
| SCHEMBL11380769 | 0.88 | LIPG (0.51) | LIPGMAPTSMN1; SMN2HSD17B10KCNH3 | |
| SCHEMBL14785273 | 0.85 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C9LIPGPOLB | |
| SCHEMBL9754655 | 0.84 | KCNH3 (0.49) | CYP2D6CYP2C9LIPGMAPTGAA | |
| SCHEMBL4015380 | 0.84 | SMN1; SMN2 (0.40) | CYP3A4CYP2D6CYP2C9LIPGPOLB | |
| SCHEMBL2493912 | 0.83 | LIPG (0.50) | LIPGMAPTGAATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642028-B2 | surface layers are a polymeric composition including a resin and a cyclic polymers such as polyethylene terephthalate, acrylic acid-ethylene copolymer, styrene-co-maleic anhydride copolymer; polyhexamethylene adipamide etc. and cyclic poly(bisphenol A carbonate), cyclic poly(bisphenol C carbonate) etc. | XEROX CORPORATION (US) | 2010-01-05 | — | — | US | claimed |
| US-20060210894-A1 | Imaging members | XEROX CORPORATION | 2006-09-21 | — | — | US | claimed |