Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010086 | 0.88 | ATM (0.46) | DHPSNAMPTMAPTLMNAALDH1A1 | |
| SCHEMBL4007716 | 0.86 | ADORA3 (0.39) | NAMPTMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL8024878 | 0.83 | NAMPT (0.40) | NAMPTMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL8024898 | 0.81 | MAPT (0.40) | NAMPTMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL4009344 | 0.80 | NPSR1 (0.39) | NAMPTMAPTLMNAALDH1A1ADORA3 | |
| SCHEMBL4009395 | 0.77 | CNR1 (0.41) | NAMPTCNR1 | |
| SCHEMBL4007708 | 0.76 | CYP1A2 (0.40) | DHPSNAMPTMAPTADORA3CYP1A2 | |
| SCHEMBL4007862 | 0.76 | NAMPT (0.38) | NAMPTMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL4007725 | 0.75 | ADORA3 (0.39) | NAMPTMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL4008512 | 0.74 | MAPT (0.42) | DHPSMAPTLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |